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Scientists are developing a pill that mimics the benefits of exercise. This pill uses a variety of chemical compounds to recreate the health benefits you get from exercise. This can be useful for people who do not have time to exercise, feel lazy or have physical limitations. However, scientists emphasize that physical exercise is still very important and cannot be completely replaced.
Who can benefit from the pill?
Expert Elgendy's team of researchers hopes to replicate the physical effects of exercise, which can offset muscle atrophy and weakness that can occur as people age, help those affected by cancer or other conditions that make them unable to stay physically active.
According to Elgendy, this type of pill can also counteract the fat-gaining effects that often cause muscle loss.
"These drug targets are elusive, and if we are successful in targeting them, this could lead to the development of therapies for some of the most challenging diseases we are facing today, such as neurodegenerative diseases and heart failure. .A lot of people like me are lazy and don't like exercise or are busy all the time so if we can solve this with a pill.Again I'm not promoting exercise replacement or anything but at least for people who are lazy like me, they can benefit from these drugs. Children who can't move from conditions like Duchenne muscle wasting can also benefit from a pill that mimics the effects of exercise," Elgendy said.
How does exercise affect the body?
After a decade of work, Elgendy and his team developed a compound called SLU-PP-332, which activates specialized estrogen-related receptor (ERR) proteins. This compound specifically activates ERRα, one of the most challenging forms of estrogen to activate. Experiments in mice showed that SLU-PP-332 increases a type of fatigue-resistant muscle fiber and improves endurance in animals running on a rodent treadmill. The researchers identified SLU-PP-332 by examining the structure of ERRs and designing their own molecules to bind more strongly to them./CNA
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