Genetics account for up to 55% of lifespan

People are often told that eating well, exercising, and avoiding bad habits are the foundations of a long life. But new research suggests that something else may matter even more: genetics.

A large study published Jan. 29 in the journal Science suggests that genetics may account for up to 55% of a person's lifespan. That's much higher than previous estimates, which ranged from 6% to 33%.

The researchers reached this conclusion by studying twins and separating deaths caused by external factors such as accidents or infections from deaths related to internal aging, such as chronic diseases or natural health deterioration.

By doing so, they said they were able to get a clearer picture of the relationship between genetics and longevity.

The study also supports previous research showing that people who live to be 100 often have genes that reduce the risk of chronic diseases.

So far, only a few genes, FOXO3, APOE and SIRT6, have been linked to longevity. The researchers said that longevity is likely dictated by many genes working together, not just one.

However, the researchers stressed that lifestyle is critical. If genetics explains 55%, that leaves 45% affected by things like diet, exercise and habits./ CNA

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